Uwe Rösler
Freie Universität Berlin
School of Veterinary Medicine
Centre for Infection Medicine & Veterinary Centre for Resistance Research (TZR)
Institute for Animal Hygiene and Environmental Health
Berlin, Germany

KEYNOTE SESSION: RESISTENCE CHALLENGES IN PIG HEALTH MANAGEMENT

``Future threats regarding resistance beyond AMR``

FRIDAY, JUNE 2, 2023

BIOSKETCH
Education

2021  Recognition as Diplomate of the European College of Veterinary Microbiology (Dipl. ECVM)

2008  Recognition as Diplomate of the European College of Porcine Health Management (Dipl. ECPHM)

2008  Recognition as German veterinary specialist (Fachtierarzt) in Epidemiology

2007  Thesis (Habilitation, Dr. med. vet. habil) and license to teach (venia legendi) in Animal Hygiene, Microbiology and Epizootics at the Institute for Veterinary Public Health of the University of Leipzig, Leipzig, Germany; Mentors: Prof. Dr. Dr. Andreas Hensel & Prof. Dr. Uwe Truyen, Dipl. ECVM

2003  Recognition as German veterinary specialist (Fachtierarzt) in Veterinary Microbiology

2002  Recognition as German veterinary specialist (Fachtierarzt) in Animal Hygiene

2001  Thesis (Dr. med. vet.) in Veterinary Microbiology and Animal Hygiene at the Institute for Veterinary Public Health of the University of Leipzig, Leipzig, Germany; Supervisor: Prof. Dr. Dr. Andreas Hensel

1997  Approbation in veterinary medicine, DVM (University of Leipzig, Leipzig, Germany)

 

Professional Activities and Academic appointments

Since 2021: Dean, Department for Veterinary Medicine, Freie Universitaet Berlin

Since 2019: Deputy Head of the FAO Reference Centre for Antimicrobial Resistance at the Department for Veterinary Medicine, Freie Universitaet Berlin

2019 -2021: Dean for Research, Department for Veterinary Medicine, Freie Universitaet Berlin

2015 – 2019: Spokesperson of the “Veterinary Centre for Resistance Research” (TZR) at the Department for Veterinary Medicine, Freie Universitaet Berlin

Since 2014: Guest Professorship (Animal Hygiene and International Veterinary Public Health) at the College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai´an

2012: Appointment as Professor (W3) for Animal Hygiene and Animal Welfare, Veterinary University Hanover, Germany – declined

Since 2008: Professor (W3) of Animal Hygiene and Infectiology, Department of Veterinary Medicine, Freie Universität Berlin, Germany; Managing Director of the Institute for Animal Hygiene and Environmental Health (ITU)

2008: Appointment as Professor (W3) for Animal Hygiene, University of Hohenheim, Stuttgart, Germany – declined

2007: Appointment as Professor (W1) for Animal Hygiene, Christian-Albrechts-University Kiel, Germany – declined

2001-2007: Postdoc at the at the Institute for Veterinary Public Health of the University of Leipzig, Leipzig, Germany (Prof. Dr. Dr. Andreas Hensel, Prof. Dr. Uwe Truyen, Dipl. ECVM)

1997-2001: PhD student at the University of Leipzig, Germany

 

Membership of Scientific Organizations

  • German Veterinary Medical Society (DVG)
    • Head of Commission for disinfection, since 2015
    • Deputy Head of Section Animal and Environmental Hygiene
  • National Research Platform for Zoonoses
  • International Society for Animal Hygiene (ISAH)
    • Member of executive board
    • Pre-elected President from 2022
  • German veterinary association for animal welfare
  • 2008 -2021, Member of the Commission for Biological Hazards (BfR – German Federal Institute for Risk Assessment)
  • Member of the Commission for Vaccination in Veterinary Medicine (FLI – German Federal Institute for Animal Heath), Expert group for Pigs

 

Colleges:
since 2021: European College of Veterinary Microbiology (Dipl. ECVM)
Since 2008: European College of Porcine Health Management (Dipl. ECPHM)

 

Honours

2007: “Stockmeyer Science award” of the Stockmeyer foundation (Food safety)

2002: “Ellenberger award” for the best Veterinary Ph.D. thesis of the Universität Leipzig

 

Bibliography

186 in international scientific journals with peer-review, more than 200  oral/poster presentations at national and international scientific conferences (12.01.2022)

– H-index: 46 (Google Scholar, 12.01.2022)

– Citations: 6270 (Google Scholar, 12.01.2022)

– ORCID ID: 0000-0002-6268-5207

 

Major research interests

  • Resistances against antibiotics, disinfectants and herbicides; epidemiology and intervention measures
  • Intervention measures against Zoonoses (eg. Salmonella, Yersinia, Campylobacter) including disinfection strategies, biosecurity measures and vaccination strategies

ABSTRACT
Resistance against anti-infectives is currently one of the biggest problems for the health of livestock and humans, and also a serious One Health issue. In this context, antibiotic resistance is receiving the most attention. In pigs, this applies to both important pig-specific pathogens, such as respiratory or enteric pathogens, but also to important zoonotic pathogens, such as salmonellae. In addition, commensal skin, mucosa and gut colonizers can carry a variety of antibiotic resistances and become a major problem for exposed immunocompromised animals and humans or those on antibiotic therapy. MRSA, ESBL-forming or colistin-resistant enterobacteria are prominent examples.

However, in addition to chromosomally encoded antibiotic resistances or antibiotic resistances encoded on mobile genetic elements, other resistance phenomena are also playing an increasing role. For example, phenotypic adaptation processes or persister cell formation are increasingly in the focus of Antibiotic resistance research. In addition to resistance to antibiotics, however, there are also numerous reports of resistance to other groups of antimicrobial agents. Disinfectants and antiseptics are the first to be listed here, but also resistance to certain herbicides. Finally, antiparasitic agents also trigger microevolutionary adaptation processes and thus induce resistances, and even against vaccines, pathogens have now found ways to effectively evade the specific vaccination response.